Neurons That Predict Your Mistakes
A biomimetic model of the corticostriatal loop discovered neurons that predict errors before they happen. About 20% of the population are "incongruent" — their activity doesn't match the dominant signal. When researchers checked real animal data, the same pattern was hiding there, overlooked for years. These neurons maintain alternatives, enabling cognitive flexibility when the world changes.
Pathak et al. — Nature Communications, Dec 2025
Watch: trials run, incongruent neurons (red) predict errors | Click: toggle learning phase | Space: pause | I: info